This policy setting allows you to configure definition updates on startup when there is no antimalware engine present. If you enable or do not configure this setting, definition updates will be initiated on startup when there is no antimalware engine present. If you disable this setting, definition updates will not be initiated on startup when there is no antimalware engine present. Fix: (1) GPO: Computer Configuration\Administrative Templates\Windows Components\Windows Defender\Signature Updates!Initiate definition update on startup (2) REG: HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows Defender\Signature Updates!DisableUpdateOnStartupWithoutEngine