The "Launching applications and files in an IFRAME" current user setting should be configured correctly for the Restricted Sites Zone. enabled/disabled User Configuration\Administrative Templates\Windows Components\Internet Explorer\Internet Control Panel\Security Page\Restricted Sites Zone\Launching applications and files in an IFRAME HKEY_CURRENT_USER\Software\Policies\Microsoft\Windows\CurrentVersion\Internet Settings\Zones\4 Microsoft Tool: Security Compliance Manager (SCM) Microsoft Baseline: Internet Explorer 8 SCM URL: http://go.microsoft.com/fwlink/?LinkId=113940 Microsoft Security Compliance Manager (SCM) Baselines and Settings Packs Microsoft